HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 24875218, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | HCID 59457539 | HCID 59457539 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 24875218 | HCID 24875218 | — |
Reaction Steps
The title compound is prepared from 5-cyano-1H-imidazole-2-carboxylic acid [2-(4,4-dimethyl-cyclohex-1-enyl)-6-(1-hydroxy-1-methyl-ethyl)-pyridin-3-yl]-amide (as prepared in Example 56, step (e)), N-methylpiperizine and thionyl chloride in DCM solvent according to the procedure in Example 14, step (e).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09221797B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-a6bb873287f24effbc1c4a9a04f4dac6 |
| Source note | uspto-grants-2015_12 |