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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1508130Generated: November 2, 2026

Morpholine → HCID 24875219, compound

https://huagongshe.com/reaction/1508130

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
ReactantThionyl ChlorideHCID 24386—
ReactantHCID 59457539HCID 59457539—
SolventDichloromethaneHCID 6344—
ProductHCID 24875219HCID 24875219—

Reaction Steps

The title compound is prepared from 5-cyano-1H-imidazole-2-carboxylic acid [2-(4,4-dimethyl-cyclohex-1-enyl)-6-(1-hydroxy-1-methyl-ethyl)-pyridin-3-yl]-amide (as prepared in Example 56, step (e)), morpholine, and thionyl chloride in DCM solvent according to the procedure in Example 14, step (e).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09221797B2
Source datasetuspto-grants-2015_12
ORD IDord-f6bcecc71c11494283b9dd9b3546b9f6
Source noteuspto-grants-2015_12