Ethyl 3-chloroisonicotinate → Ethyl 3-hydroxyfuro[2,3-c]pyridine-2-carboxylate

HRID 1508197Notes

Reaction equation

HRID 1508197 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[O:14][C:9]2N=[N:11][CH:12]=[CH:13][C:8]=2[C:7]=1[OH:15])=[O:5])[CH3:2].[CH2:16](OC(=O)C1C=CN=CC=1Cl)C>>[CH2:1]([O:3][C:4]([C:6]1[O:14][C:9]2=[CH:16][N:11]=[CH:12][CH:13]=[C:8]2[C:7]=1[OH:15])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 2762498Ethyl 3-chloroisonicotinateHCID 71239586HCID 71239586, compound

Product 1

HCID 54723934Ethyl 3-hydroxyfuro[2,3-c]pyridine-2-carboxylate

Procedure

This compound was prepared using a method analogous to that of 5-hydroxyfuro[2,3-c]pyridazine-6-carboxylic acid ethyl ester (A.2.3.1), 3-chloroisonicotinic acid ethyl ester replacing 3-chloropyridazine-4-carboxylic acid ethyl ester;

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-6a0136b3c7ab45d78397a853de1c4788
Source dataset
uspto-grants-2015_12
Patent number
US09221832B2

Reaction notes

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