Furo[2,3-C]pyridin-3(2H)-one → 7-methylfuro[2,3-c]pyridin-3(2H)-one

HRID 1508204Notes

Reaction equation

HRID 1508204 reaction equation
O1C2=CN=CC=C2C(=O)C1.C(OC([C:16]1[O:25][C:19]2=[C:20]([CH3:24])[N:21]=[CH:22][CH:23]=[C:18]2[C:17]=1[OH:26])=O)C>>[CH3:24][C:20]1[N:21]=[CH:22][CH:23]=[C:18]2[C:17](=[O:26])[CH2:16][O:25][C:19]=12

Participants

3

Reactant 2

HCID 14199080Furo[2,3-C]pyridin-3(2H)-oneHCID 712394593-Hydroxy-7-methylfuro[2,3-c]pyridine-2-carboxylic acid ethyl ester

Product 1

HCID 867219067-methylfuro[2,3-c]pyridin-3(2H)-one

Procedure

This compound was prepared using a method analogous to that of furo[2,3-c]pyridin-3(2H)-one (A.2.4.3), 3-hydroxy-7-methylfuro[2,3-c]pyridine-2-carboxylic acid ethyl ester replacing 3-hydroxyfuro[2,3-c]pyridine-2-carboxylic acid ethyl ester;

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-58d84dd07f3044ae93e22230c48a84fe
Source dataset
uspto-grants-2015_12
Patent number
US09221832B2

Reaction notes

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