Furo[2,3-C]pyridin-3(2H)-one → 7-cyclopropylfuro[2,3-c]pyridin-3(2H)-one

HRID 1508209Notes

Reaction equation

HRID 1508209 reaction equation
O1C2=CN=CC=C2C(=O)C1.C(OC([C:16]1[O:27][C:19]2=[C:20]([CH:24]3[CH2:26][CH2:25]3)[N:21]=[CH:22][CH:23]=[C:18]2[C:17]=1[OH:28])=O)C>>[CH:24]1([C:20]2[N:21]=[CH:22][CH:23]=[C:18]3[C:17](=[O:28])[CH2:16][O:27][C:19]=23)[CH2:26][CH2:25]1

Participants

3

Reactant 2

HCID 14199080Furo[2,3-C]pyridin-3(2H)-oneHCID 71239378HCID 71239378, compound

Product 1

HCID 867219097-cyclopropylfuro[2,3-c]pyridin-3(2H)-one

Procedure

This compound was prepared using a method analogous to that of furo[2,3-c]pyridin-3(2H)-one (A.2.4.3), 3-hydroxy-7-cyclopropylfuro[2,3-c]pyridine-2-carboxylic acid ethyl ester replacing 3-hydroxyfuro[2,3-c]pyridine-2-carboxylic acid ethyl ester;

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-66810902734748cb959db87834c43e02
Source dataset
uspto-grants-2015_12
Patent number
US09221832B2

Reaction notes

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