Furo[2,3-C]pyridin-3(2H)-one → 6-Methyl-furo[2,3-B]pyridin-3-one

HRID 1508232Notes

Reaction equation

HRID 1508232 reaction equation
O1C2=CN=CC=C2C(=O)C1.C(OC([C:16]1[O:25][C:19]2=[N:20][C:21]([CH3:24])=[CH:22][CH:23]=[C:18]2[C:17]=1[OH:26])=O)C>>[CH3:24][C:21]1[N:20]=[C:19]2[O:25][CH2:16][C:17](=[O:26])[C:18]2=[CH:23][CH:22]=1

Participants

3

Reactant 2

HCID 14199080Furo[2,3-C]pyridin-3(2H)-oneHCID 712395013-Hydroxy-6-methylfuro[2,3-b]pyridine-2-carboxylic acid ethyl ester

Product 1

HCID 722126836-Methyl-furo[2,3-B]pyridin-3-one

Procedure

This compound was prepared using a method analogous to that of furo[2,3-c]pyridin-3(2H)-one (A.2.4.3), 3-hydroxy-6-methylfuro[2,3-b]pyridine-2-carboxylic acid ethyl ester replacing 3-hydroxyfuro[2,3-c]pyridine-2-carboxylic acid ethyl ester;

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-8bfaa3aaca1c411d99fdc4136c45ffa5
Source dataset
uspto-grants-2015_12
Patent number
US09221832B2

Reaction notes

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