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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1508250Generated: October 30, 2026

Ethyl 2-chloro-4-ethoxy-6-methylpyridine-3-carboxylate → 3-Hydroxy-4-ethoxy-6-methylfuro[2,3-b]pyridine-2-carboxylic acid ethyl ester

https://huagongshe.com/reaction/1508250

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-chloro-4-ethoxy-6-methylpyridine-3-carboxylateHCID 52911135—
ReactantHCID 71239586HCID 71239586—
Product3-Hydroxy-4-ethoxy-6-methylfuro[2,3-b]pyridine-2-carboxylic acid ethyl esterHCID 71239381—

Reaction Steps

This compound was prepared using a method analogous to that of 5-hydroxyfuro[2,3-c]pyridazine-6-carboxylic acid ethyl ester (A.2.3.1), 2-chloro-4-ethoxy-6-methylnicotinic acid ethyl ester replacing 3-chloropyridazine-4-carboxylic acid ethyl ester;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09221832B2
Source datasetuspto-grants-2015_12
ORD IDord-1ba7b0ee80be48ccb086a01ade0ed016
Source noteuspto-grants-2015_12