Furo[2,3-C]pyridin-3(2H)-one → 4-ethoxy-6-methylfuro[2,3-b]pyridin-3(2H)-one

HRID 1508251Notes

Reaction equation

HRID 1508251 reaction equation
O1C2=CN=CC=C2C(=O)C1.C(OC([C:16]1[O:28][C:19]2=[N:20][C:21]([CH3:27])=[CH:22][C:23]([O:24][CH2:25][CH3:26])=[C:18]2[C:17]=1[OH:29])=O)C>>[CH2:25]([O:24][C:23]1[CH:22]=[C:21]([CH3:27])[N:20]=[C:19]2[O:28][CH2:16][C:17](=[O:29])[C:18]=12)[CH3:26]

Participants

3

Reactant 2

HCID 14199080Furo[2,3-C]pyridin-3(2H)-oneHCID 712393813-Hydroxy-4-ethoxy-6-methylfuro[2,3-b]pyridine-2-carboxylic acid ethyl ester

Product 1

HCID 867219394-ethoxy-6-methylfuro[2,3-b]pyridin-3(2H)-one

Procedure

This compound was prepared using a method analogous to that of furo[2,3-c]pyridin-3(2H)-one (A.2.4.3), 3-hydroxy-4-ethoxy-6-methylfuro[2,3-b]pyridine-2-carboxylic acid ethyl ester replacing 3-hydroxyfuro[2,3-c]pyridine-2-carboxylic acid ethyl ester;

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-6d39b3238a9e4238b7396a215dd134ac
Source dataset
uspto-grants-2015_12
Patent number
US09221832B2

Reaction notes

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