5,6-Dihydrofuro[2,3-c]pyridazin-5-amine → 4-Ethoxy-6-methyl-2,3-dihydrofuro[2,3-b]pyridin-3-amine

HRID 1508253Notes

Reaction equation

HRID 1508253 reaction equation
N1C2OCC(N)C=2C=CN=1.CO[N:13]=[C:14]1[C:22]2[C:17](=[N:18][C:19]([CH3:26])=[CH:20][C:21]=2[O:23][CH2:24][CH3:25])[O:16][CH2:15]1>>[CH2:24]([O:23][C:21]1[CH:20]=[C:19]([CH3:26])[N:18]=[C:17]2[O:16][CH2:15][CH:14]([NH2:13])[C:22]=12)[CH3:25]

Participants

3

Reactant 2

HCID 867219025,6-Dihydrofuro[2,3-c]pyridazin-5-amineHCID 867219404-ethoxy-6-methylfuro[2,3-b]pyridin-3(2H)-one O-methyl oxime

Product 1

HCID 867219414-Ethoxy-6-methyl-2,3-dihydrofuro[2,3-b]pyridin-3-amine

Procedure

This compound was prepared using a method analogous to that of 5,6-dihydrofuro[2,3-c]pyridazin-5-amine (A.2.3.4), 4-ethoxy-6-methylfuro[2,3-b]pyridin-3(2H)-one O-methyl oxime replacing furo[2,3-c]pyridazin-5(6H)-one O-methyl oxime;

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-40a2b24ab57e435995377ece8fc7f3e8
Source dataset
uspto-grants-2015_12
Patent number
US09221832B2

Reaction notes

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