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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1508255Generated: October 30, 2026

2-Chloro-4-methoxy-6-methylnicotinic acid ethyl ester → 3-Hydroxy-4-methoxy-6-methylfuro[2,3-b]pyridine-2-carboxylic acid ethyl ester

https://huagongshe.com/reaction/1508255

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4-methoxy-6-methylnicotinic acid ethyl esterHCID 13933642—
ReactantHCID 71239586HCID 71239586—
Product3-Hydroxy-4-methoxy-6-methylfuro[2,3-b]pyridine-2-carboxylic acid ethyl esterHCID 71239392—

Reaction Steps

This compound was prepared using a method analogous to that of 5-hydroxyfuro[2,3-c]pyridazine-6-carboxylic acid ethyl ester (A.2.3.1), 2-chloro-4-methoxy-6-methylnicotinic acid ethyl ester replacing 3-chloropyridazine-4-carboxylic acid ethyl ester;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09221832B2
Source datasetuspto-grants-2015_12
ORD IDord-d22ceab280c049e79fb3c0c86181a327
Source noteuspto-grants-2015_12