Ethyl 2-chloro-4-(trifluoromethyl)pyridine-3-carboxylate → HCID 71239363, compound

HRID 1508259Notes

Reaction equation

HRID 1508259 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[O:14]C2N=NC=CC=2C=1O)=[O:5])[CH3:2].C(O[C:19](=[O:31])[C:20]1[C:25]([C:26]([F:29])([F:28])[F:27])=[CH:24][CH:23]=[N:22][C:21]=1Cl)C>>[CH2:1]([O:3][C:4]([C:6]1[O:14][C:21]2=[N:22][CH:23]=[CH:24][C:25]([C:26]([F:27])([F:28])[F:29])=[C:20]2[C:19]=1[OH:31])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 50853190Ethyl 2-chloro-4-(trifluoromethyl)pyridine-3-carboxylateHCID 71239586HCID 71239586, compound

Product 1

HCID 71239363HCID 71239363, compound

Procedure

This compound was prepared using a method analogous to that of 5-hydroxyfuro[2,3-c]pyridazine-6-carboxylic acid ethyl ester (A.2.3.1), 2-chloro-4-(trifluoromethyl)nicotinic acid ethyl ester replacing 3-chloropyridazine-4-carboxylic acid ethyl ester;

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-c638d404f0de417db4fa52cd98f6f825
Source dataset
uspto-grants-2015_12
Patent number
US09221832B2

Reaction notes

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