HCID 90199358, compound → HCID 71239428, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of rac-3,5-dichloro-2-(2-((2,3-dihydrofuro[2,3-b]pyridin-3-yl)amino)-2-oxoethyl)benzyl acetate (0.097 mmol) in 0.5 mL THF and 0.24 mL of 2M NaOH solution was stirred at 30° C. for 3 h. The reaction mixture was diluted with EtOAc and washed with water and brine. The organic layer was dried over MgSO4 and concentrated in vacuo to give the desired compound as white solid.

Provenance & Evidence