HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Oxalate → Ethyl 2-oxo-3-phenylpropanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Oxalate | HCID 7268 | — |
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Magnesium | HCID 5462224 | — |
| Reactant | Ethyl (2-fluorophenyl)pyruvate | HCID 18370709 | — |
| Product | Ethyl 2-oxo-3-phenylpropanoate | HCID 12292599 | 80% |
Reaction Steps
The title compound was prepared as described for B4 using benzyl bromide (1.250 g, 7.31 mmol), magnesium (0.195 g, 8.04 mmol) and diethyl oxalate (2.136 g, 14.62 mmol) in the form of colorless oil in 80% yield and used instantly in next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09221860B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-52eb95a6d9b74cc5876a983ee0b66d2d |
| Source note | uspto-grants-2015_12 |