HCID 67513886, compound → HCID 67513794, compound

Participants

Reaction Steps

Methyl 4′-ethenyl-2-methyl-3′-nitrobiphenyl-4-carboxylate (1.6206 g, 5.45 mmol), palladium on carbon (0.290 g, 0.273 mmol) and MeOH (50 mL) were stirred under a balloon atmosphere of H2 at room temperature overnight. The reaction crude was filtered and concentrated in vacuo to afford a light yellow oil. The resulting oil was purified by flash chromatography (SiO2, Biotage SNAP Cartridge, silica gel 100 g cartridge). The column was eluted by an EtOAc/hexanes mixture (0% to 40%). Related fractions were pooled and evaporated to afford a light yellow oil as the titled compound. LCMS calc.=269.14. found=270.30 (M+H)+.

Provenance & Evidence