HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Pyridone → 4-[(5-Chloro-2-pyridinyl)methoxy]-1-(4-{[(2S)-1-ethyl-2-pyrrolidinyl]-methoxy}phenyl)-1H-pyridin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Pyridone | HCID 8871 | — |
| Reactant | 4-[(5-Chloro-2-pyridinyl)methoxy]-1-(4-{[(2S)-2-pyrrolidinyl]methoxy}phenyl)-1H-pyridin-2-one | HCID 58964952 | — |
| Product | 4-[(5-Chloro-2-pyridinyl)methoxy]-1-(4-{[(2S)-1-ethyl-2-pyrrolidinyl]-methoxy}phenyl)-1H-pyridin-2-one | HCID 11597352 | — |
Reaction Steps
Example 123 was repeated except that 4-[(5-chloro-2-pyridinyl)methoxy]-1-4-{(3R)-3-pyrrolidinyl]oxy}phenyl)-2H-pyridin-2-one was replaced with 4-[(5-chloro-2-pyridinyl)methoxy]-1-(4-{[(2S)-2-pyrrolidinyl]methoxy}phenyl)-1H-pyridin-2-one, to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07732456B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-649ebafba1b641aeb7be4a1cd45faf2a |
| Source note | uspto-grants-2010_06 |