Methanol → 7-Bromo-3-methyl-1,2,3,4-tetrahydroisoquinoline

HRID 150908Notes

Reaction equation

HRID 150908 reaction equation
[Br:6][c:7]1[cH:8][cH:9][c:10]2[c:15]([cH:16]1)[CH2:14][N:13]([C:17]([O:18][CH3:19])=[O:20])[CH:12]([CH3:21])[CH2:11]2.[CH2:24]([Cl:25])[Cl:26].[CH3:22][OH:23].[I:1][Si:2]([CH3:3])([CH3:4])[CH3:5]>>[Br:6][c:7]1[cH:8][cH:9][c:10]2[c:15]([cH:16]1)[CH2:14][NH:13][CH:12]([CH3:21])[CH2:11]2

Participants

5

Reactant 4

HCID 887MethanolHCID 6344DichloromethaneHCID 85247Trimethylsilyl iodideHCID 59402311HCID 59402311, compound

Product 1

HCID 444054957-Bromo-3-methyl-1,2,3,4-tetrahydroisoquinoline

Sources & evidence

ORD record
ord-ac230daf95d1481588e548b6fdbecc40
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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