2-(4-(1-aminocyclobutyl)phenyl)-3-phenyl-7,8-dihydroquinolin-5(6H)-one → HCID 53261988, compound

Participants

Reaction Steps

Following the procedure for 2-(4-(1-aminocyclobutyl)phenyl)-3-phenyl-7,8-dihydroquinolin-5(6H)-one, tert-butyl(1-(4-(2-oxo-7-phenyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-6-yl)phenyl)cyclobutyl)carbamate (8 mg, 0.017 mmol) was reacted to afford the title compound (6 mg, 73%). LCMS (Method A): RT=3.59 min, M+1=373. 1H NMR (500 MHz, MeOD): 7.40 (2H, d), 7.37 (2H, d), 7.33 (1H, s), 7.32-7.28 (3H, m), 7.19-7.17 (2H, m), 4.93 (2H, s), 2.78-2.72 (2H, m), 2.60-2.54 (2H, m), 2.27-2.19 (1H, m), 2.00-1.91 (1H, m).

Provenance & Evidence