2-(4-(1-aminocyclobutyl)phenyl)-3-phenyl-7,8-dihydroquinolin-5(6H)-one → HCID 67256718, compound

Participants

Reaction Steps

Following the procedure for 2-(4-(1-aminocyclobutyl)phenyl)-3-phenyl-7,8-dihydroquinolin-5(6H)-one, tert-butyl(1-(4-(7-phenyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-6-yl)phenyl)cyclobutyl)carbamate (15 mg, 0.03 mmol) was reacted to afford the title compound (15 mg, quantitative). LCMS (Method A): RT=3.80 min, M-NH2=341. 1H NMR (500 MHz, MeOD): 7.31 (4H, s), 7.22-7.21 (3H, m), 7.12-7.11 (2H, m), 7.01 (1H, s), 4.45 (2H, t), 3.45 (2H, t), 2.75-2.70 (m, 2H), 2.56-2.50 (m, 2H), 2.24-2.15 (m, 1H), 1.97-1.88 (m, 1H).

Provenance & Evidence