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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1509251Generated: November 2, 2026

1-Bromo-2-methylpropane → HCID 131734405, compound

https://huagongshe.com/reaction/1509251

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-2-methylpropaneHCID 6555—
ReactantHCID 67256382HCID 67256382—
Reactanttert-butyl(1-(4-(1-(2-cyanoethyl)-2-oxo-7-phenyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-6-yl)phenyl)cyclobutyl)carbamateHCID 123769430—
ProductHCID 131734405HCID 131734405—

Reaction Steps

Following the procedure for tert-butyl(1-(4-(1-(2-cyanoethyl)-2-oxo-7-phenyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-6-yl)phenyl)cyclobutyl)carbamate, tert-butyl 1-(4-(2-oxo-7-phenyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-6-yl)phenyl)cyclobutylcarbamate (100 mg, 0.212 mmol) was reacted with 1-bromo-2-methylpropane (87 mg, 0.636 mmol) to afford the title compound (78 mg). LCMS (method D) RT=1.73 min, M+H=528.2

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09221838B2
Source datasetuspto-grants-2015_12
ORD IDord-ca0131e20e604c0d99bc2bec8b6283e6
Source noteuspto-grants-2015_12