HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-2-methylpropane → HCID 131734405, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-2-methylpropane | HCID 6555 | — |
| Reactant | HCID 67256382 | HCID 67256382 | — |
| Reactant | tert-butyl(1-(4-(1-(2-cyanoethyl)-2-oxo-7-phenyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-6-yl)phenyl)cyclobutyl)carbamate | HCID 123769430 | — |
| Product | HCID 131734405 | HCID 131734405 | — |
Reaction Steps
Following the procedure for tert-butyl(1-(4-(1-(2-cyanoethyl)-2-oxo-7-phenyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-6-yl)phenyl)cyclobutyl)carbamate, tert-butyl 1-(4-(2-oxo-7-phenyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-6-yl)phenyl)cyclobutylcarbamate (100 mg, 0.212 mmol) was reacted with 1-bromo-2-methylpropane (87 mg, 0.636 mmol) to afford the title compound (78 mg). LCMS (method D) RT=1.73 min, M+H=528.2
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09221838B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-ca0131e20e604c0d99bc2bec8b6283e6 |
| Source note | uspto-grants-2015_12 |