HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen chloride-ethyl acetate → HCID 67321792, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen chloride-ethyl acetate | HCID 21866389 | — |
| Reactant | HCID 58355330 | HCID 58355330 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 67321792 | HCID 67321792 | — |
Reaction Steps
tert-Butyl (3S,5R)-3-[{[1-(4-methoxybutyl)-5-phenyl-1H-pyrrol-2-yl]carbonyl}(2-methylpropyl)amino]-5-(morpholin-4-ylcarbonyl)piperidine-1-carboxylate (150 mg) was dissolved in ethyl acetate (5 ml), 4N hydrogen chloride-ethyl acetate (5 ml) was added and the mixture was stirred for 1 hr. The solvent was evaporated under reduced pressure to give the object product (110 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09221836B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-280826279ae54e37a95a139ee30b9faf |
| Source note | uspto-grants-2015_12 |