HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Aminosalicylic Acid → HCID 9949494, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Aminosalicylic Acid | HCID 4075 | — |
| Reactant | Pentafluorobenzyl bromide | HCID 74484 | — |
| Product | HCID 9949494 | HCID 9949494 | 60% |
Reaction Steps
By following the similar procedure in Synthesis Example 1 by using 5-aminosalicylic acid (500 mg, 3.26 mmole) and pentafluorobenzyl bromide (1.02 g, 3.92 mmole), 650 mg (60% yield) of 5-(pentafluorobenzyl)aminosalicylic acid was obtained as a white solid.: mp>190° C. (decompose).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08211878B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-37bdd83f36d94255ad1c3ea222904faa |
| Source note | uspto-grants-2012_07 |