5-Chlorosalicylic Acid → HCID 29032327, compound

HRID 1509836Notes

Reaction equation

[Cl:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[CH2:12]([C:14]1[CH:15]=[C:16]([CH:18]=[CH:19][CH:20]=1)[NH2:17])[CH3:13]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:17][C:16]1[CH:18]=[CH:19][CH:20]=[C:14]([CH2:12][CH3:13])[CH:15]=1)=[O:9]

Participants

Reactant 2

HCID 94475-Chlorosalicylic Acid

HCID 114753-Ethylaniline

Product 1

HCID 29032327HCID 29032327, compound

Procedure

This material was prepared according to the method of Example 1 using 5-chlorosalicylic acid and 3-ethylaniline, with reagents and solvents employed in similar molar ratios. 1HNMR (500 MHz, DMSO-d6): δ 1.20 (t, 3H), 2.62 (q, 1H), 7.02 (m, 2H), 7.28 (m, 1H), 7.47 (m, 1H), 7.54 (m, 1H), 7.56 (br s, 1H), 7.90 (m, 1H), 10.34 (s, 1H).

Workup

customThis material was prepared

Sources & evidence

ORD record: ord-9ad6a617d9cf491f86cecb0d7b628fe5
Source dataset: uspto-grants-2012_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08211882B2

Reaction notes

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