HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methoxybenzenesulfonyl chloride → N-[4-Bromo-2-(pyridine-4-carbonyl)-phenyl]4-methoxy-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methoxybenzenesulfonyl chloride | HCID 7401 | — |
| Reactant | (2-Amino-5-bromophenyl)(pyridin-4-yl)methanone | HCID 13549724 | — |
| Product | N-[4-Bromo-2-(pyridine-4-carbonyl)-phenyl]4-methoxy-benzenesulfonamide | HCID 10049261 | — |
Reaction Steps
The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using 138 mg of (2-amino-5-bromo-phenyl)-pyridin-4-yl-methanone and 101 mg of 4-methoxy-benzenesulfonyl chloride. 1H-NMR (400 MHz, CDCl3): δ 3.69 (s, 3H), 6.68 (d, 2H, J=8.8 Hz), 7.36-7.47 (m, 4H), 7.46, 7.55-7.69 (m, 5H), 9.65 (s, 1H). MS: m/z 448.3 (M++1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08211896B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-728e0c2f99f049b49a57204adb83eb47 |
| Source note | uspto-grants-2012_07 |