Ethyl bromoacetate → HCID 57687138, compound

Participants

Reaction Steps

18-Crown-6 (1.069 g, 4.05 mmol), 2,5-dimethoxy-3-hydroxynitrobenzene (0.961 g, 4.05 mmol) and ethyl bromoacetate (0.449 ml, 4.05 mmol) were stirred at RT for 18 h. The reaction mixture was then concentrated in vacuo and the residue was purified by column chromatography eluting with 10-15% EtOAc in Isohexanes to afford the title compound (881 mg, 76%). m/z 286 [M+H]+.

Provenance & Evidence