2-chloro-1H-indole-3-carbaldehyde → HCID 86035948, compound

HRID 1510069Notes

Reaction equation

HRID 1510069 reaction equation
[Cl:1][C:2]1[NH:3][C:4]2[C:9]([C:10]=1[CH:11]=[O:12])=[CH:8][CH:7]=[CH:6][CH:5]=2.[S:13]1[CH:17]=[CH:16][C:15](B(O)O)=[CH:14]1>>[Cl:1][C:2]1[N:3]([C:15]2[CH:16]=[CH:17][S:13][CH:14]=2)[C:4]2[C:9]([C:10]=1[CH:11]=[O:12])=[CH:8][CH:7]=[CH:6][CH:5]=2

Participants

3

Reactant 2

HCID 3147912-chloro-1H-indole-3-carbaldehydeHCID 581760Thiophene-3-boronic acid

Product 1

HCID 86035948HCID 86035948, compound

Procedure

The title compound was prepared analogously as described in example 9, step 2, using 2-chloro-1H-indole-3-carbaldehyde (300 mg, 1.67 mmol) and thiophene-3-boronic acid. Yield: 123 mg.

Sources & evidence

ORD record
ord-e38caf1ed10d4c9a8080682af5e251fc
Source dataset
uspto-grants-2012_07
Patent number
US08211885B2

Reaction notes

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