3-Fluoro-2-methylphenol → HCID 66920279, compound

HRID 1510070Notes

Reaction equation

HRID 1510070 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][N:11]([C:14]([C:16]2[C:24]3[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=3)[N:18]([C:25]3[CH:29]=[CH:28][S:27][CH:26]=3)[C:17]=2Cl)=[O:15])[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[F:31][C:32]1[C:33]([CH3:39])=[C:34]([OH:38])[CH:35]=[CH:36][CH:37]=1>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][N:11]([C:14]([C:16]2[C:24]3[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=3)[N:18]([C:25]3[CH:29]=[CH:28][S:27][CH:26]=3)[C:17]=2[O:38][C:34]2[CH:35]=[CH:36][CH:37]=[C:32]([F:31])[C:33]=2[CH3:39])=[O:15])[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 3026283-Fluoro-2-methylphenolHCID 66920293HCID 66920293, compound

Product 1

HCID 66920279HCID 66920279, compound

Procedure

From the compound of step 3 (50 mg, 112 μmol), the title compound was prepared analogously as described in example 1, step 2, using 3-fluoro-2-methylphenol. Yield: 11 mg.

Sources & evidence

ORD record
ord-22ec4c90520746b7a131ae4698b65f70
Source dataset
uspto-grants-2012_07
Patent number
US08211885B2

Reaction notes

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