Trifluoroacetic acid → HCID 66920272, compound

Participants

Reaction Steps

The compound of step 3 (20 mg, 36 μmol) was dissolved in DCM (6 ml), TFA (2 ml) was added, and the mixture was stirred at room temperature for 1 h. The solvents were evaporated. The residue was dissolved in a small quantity of MOH, mixed with hydrochloric acid (0.1 M) and lyophilized overnight. 11 mg of the title compound were obtained in the form of the 2-(5-fluoro-2-methyl-phenoxy)-1-phenyl-3-(piperazine-1-carbonyl)-1H-indole-6-carbonitrile hydrochloride.

Provenance & Evidence