Carbon Tetrachloride → 1-(Chloromethyl)-3-(1-cyclopropylethoxy)benzene

Participants

Reaction Conditions

Reaction Steps

[3-(1-cyclopropylethoxy)phenyl]methanol (0.418 g, 2.17 mmol) in carbon tetrachloride (8.70 ml) was added triphenylphosphine resin (1.14 g, 4.35 mmol). The reaction was refluxed overnight with minimal stirring at 78° C. The next day the mixture was filtered through a fritted funnel and washed with dichloromethane. The filtrate was concentrated and no purification was necessary.

Provenance & Evidence