Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dichloromethane → (3-Isopropoxyphenyl)methanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dichloromethane | HCID 6344 | — |
| 반응물 | 3-Isopropoxybenzaldehyde | HCID 712914 | — |
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | (3-Isopropoxyphenyl)methanol | HCID 2759474 | — |
반응 단계
To a 1 molar solution of 3-isopropoxy benzaldehyde (102 g, 0.621 moles) in methanol (620 mL) cooled to 0° was added (slowly) sodium borohydride powder (25.8 g, 0.683 moles)-dissolved in a minimum of methylene chloride and passed through a plug of silica gel washing with more methylene chloride until the silica gel was free of the product. The eluent was stripped to an oil and pumped on high vacuum overnight.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08211904B2 |
| 출처 데이터셋 | uspto-grants-2012_07 |
| ORD ID | ord-bb2baadfd4414e958c89bb400d2de812 |
| 출처 메모 | uspto-grants-2012_07 |