4-Methylmorpholine → tert.-butyl(R)-2-[(5-chloro-thiophene-2-carbonyl)-amino]-propionate

Participants

Role	Name	HCID	Charge
Reactant	4-Methylmorpholine	HCID 7972	—
Reactant	O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate	HCID 2733207	—
Reactant	D-alaninate	HCID 5460978	—
Reactant	Tert.-butyl 5-chloro-thiophene-2-carboxylic acid	HCID 68637263	—
Solvent	Tetrahydrofuran	HCID 8028	—
Product	tert.-butyl(R)-2-[(5-chloro-thiophene-2-carbonyl)-amino]-propionate	HCID 68637194	—

Prepared analogously to Example 1a from tert.-butyl 5-chloro-thiophene-2-carboxylic acid and (R)-2-amino-propionate with TBTU and NMM in THF.