4-Thiazoleacetic acid, 2-amino-, ethyl ester → [2-(3-Isopropoxy-5-phenoxy-benzoylamino)-thiazol-4-yl]-acetic Acid Ethyl Ester

HRID 1510302Notes

Reaction equation

HRID 1510302 reaction equation
[NH2:1][C:2]1[S:3][CH:4]=[C:5]([CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])[N:6]=1.[CH:13]([O:16][C:17]1[CH:18]=[C:19]([CH:23]=[C:24]([O:26][C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)[CH:25]=1)[C:20](O)=[O:21])([CH3:15])[CH3:14]>>[CH2:11]([O:10][C:8](=[O:9])[CH2:7][C:5]1[N:6]=[C:2]([NH:1][C:20](=[O:21])[C:19]2[CH:23]=[C:24]([O:26][C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)[CH:25]=[C:17]([O:16][CH:13]([CH3:14])[CH3:15])[CH:18]=2)[S:3][CH:4]=1)[CH3:12]

Participants

3

Reactant 2

HCID 1044544-Thiazoleacetic acid, 2-amino-, ethyl esterHCID 669698623-Isopropyloxy-5-phenoxybenzoic acid

Product 1

HCID 24757168[2-(3-Isopropoxy-5-phenoxy-benzoylamino)-thiazol-4-yl]-acetic Acid Ethyl Ester

Procedure

The title compound was prepared from ethyl 2-aminothiazol-4-ylacetate and 3-isopropyloxy-5-phenoxybenzoic acid following synthetic description A.

Sources & evidence

ORD record
ord-a436088c9e7847b9841ad4bfc091c690
Source dataset
uspto-grants-2012_07
Patent number
US08211925B2

Reaction notes

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