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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1510307Generated: November 3, 2026

4-Thiazoleacetic acid, 2-amino-, ethyl ester → HCID 59637260, compound

https://huagongshe.com/reaction/1510307

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Thiazoleacetic acid, 2-amino-, ethyl esterHCID 104454—
Reactant(3-Methoxyphenyl)boronic acidHCID 2734370—
ReactantHCID 66970016HCID 66970016—
ProductHCID 59637260HCID 59637260—

Reaction Steps

{2-[3-(3-Methoxy-phenoxy)-5-(S)-2-methoxy-1-methyl-ethoxy)-benzoylamino]-thiazol-4-yl}acetic acid ethyl ester was prepared from 3-{(1S)-2-methoxy-(methylethyl)oxy}-5-{[3-methoxy-phenyl]oxy}benzoic acid (prepared in analogy to the method described in general synthetic descriptions F, using 3-methoxyphenylboronic acid in step D)) and ethyl 2-aminothiazol-4-ylacetate following synthetic description A.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08211925B2
Source datasetuspto-grants-2012_07
ORD IDord-933821fe09894b4185ba2461728a8fd8
Source noteuspto-grants-2012_07