HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86649454, compound → 3-[2-(3-Isopropoxy-5-phenoxybenzoylamino)-thiazol-5-yl]-propionic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86649454 | HCID 86649454 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-[2-(3-Isopropoxy-5-phenoxybenzoylamino)-thiazol-5-yl]-propionic acid ethyl ester | HCID 86649455 | 90% |
Reaction Steps
3-[2-(3-Isopropoxy-5-phenoxybenzoylamino)-thiazol-5-yl]-propionic acid ethyl ester was prepared in 90% yield from the reduction of 3-[2-(3-isopropoxy-5-phenoxybenzoylamino)-thiazol-5-yl]-acrylic acid ethyl ester in methanol (10 mL) using hydrogen (60 psi) over Pd/C (200 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08211925B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-bd6525bba22b4bfeb6d6db971137f552 |
| Source note | uspto-grants-2012_07 |