Chlorosuccinimide → HCID 67121071, Verbindung

Beteiligte Stoffe

Reaktionsschritte

A mixture of ethyl 5-(4-chlorophenyl)isoxazole-3-carboxylate (250 mg, 1.0 mmol) and N-chlorosuccinimide (267 mg, 2.0 mmol) in acetic acid (5 mL) was heated to reflux for 3 days. The reaction mixture was then allowed to cool to room temperature, poured over ice and the resulting pale yellow solid was collected, washed with portions of water, and dried to obtain ethyl 4-chloro-5-(4-chlorophenyl)isoxazole-3-carboxylate (234 mg, 0.82 mmol).

Herkunft & Nachweise