5-(4-Chlorophenyl)-4-methylisoxazole-3-carboxylic acid → HCID 25182042, compound

HRID 1510433Notes

Reaction equation

HRID 1510433 reaction equation
[Cl:1][C:2]1[C:3]([C:14]([OH:16])=O)=[N:4][O:5][C:6]=1[C:7]1[CH:12]=[CH:11][C:10]([Cl:13])=[CH:9][CH:8]=1.ClC1C=C[C:21]([C:24]2[O:28][N:27]=[C:26]([C:29](O)=O)[C:25]=2C)=CC=1>>[Cl:1][C:2]1[C:3]([C:14]([NH:27][C@@H:26]2[CH2:29][CH2:21][C@H:24]([OH:28])[CH2:25]2)=[O:16])=[N:4][O:5][C:6]=1[C:7]1[CH:8]=[CH:9][C:10]([Cl:13])=[CH:11][CH:12]=1

Participants

3

Reactant 2

HCID 671210815-(4-Chlorophenyl)-4-methylisoxazole-3-carboxylic acidHCID 671211334-Chloro-5-(4-chlorophenyl)isoxazole-3-carboxylic acid

Product 1

HCID 25182042HCID 25182042, compound

Procedure

Using 4-chloro-5-(4-chlorophenyl)isoxazole-3-carboxylic acid, synthesised according to Example 1, in place of 5-(4-chlorophenyl)-4-methylisoxazole-3-carboxylic acid.

Workup

  1. customsynthesised

Sources & evidence

ORD record
ord-efc3ece90f224424a017304b661f1fd2
Source dataset
uspto-grants-2012_07
Patent number
US08211927B2

Reaction notes

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