HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → 2,2,6,6-Tetramethylpiperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | 2,4-Diaminotoluene | HCID 7261 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Product | 2,2,6,6-Tetramethylpiperidine | HCID 13035 | — |
Reaction Steps
Four amine bases were examined (Table 2) in THF or acetonitrile. Of the 4 amines examined, 2,2,6,6-tetramethylpiperidine gave the best results in both acetonitrile and THF (72%, 65%). Piperidine, which was used in the previous method, gave a low yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08212055B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-f84de075d0444444939e624ff6c58c0c |
| Source note | uspto-grants-2012_07 |