Water → 3,5-Di-tert-butyl-4-hydroxybenzaldehyde

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Reaction Steps

2,6-di-tert-butylphenol was dissolved in glacial acetic acid. Subsequently, urotropin and water were added, and the reaction mixture heated at not more than 2° C. below the reflux temperature for 4 to 5 hours. The precipitated product was filtered off and washed with water and methanol, and dried on a rotary evaporator. The molar ratios of the reactants used and also the determined yields of 3,5-di-tert-butyl-4-hydroxybenzaldehyde, based on 2,6-di-tert-butylphenol, are shown in Table 4.

Provenance & Evidence