Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Anhydride → 4-Acetyl-6-methoxy-1H-2-benzopyran-1,3(4H)-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | L-Selenocysteine | HCID 25076 | — |
| 반응물 | 2-(Carboxymethyl)-4-methoxybenzoic acid | HCID 11816626 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 4-Acetyl-6-methoxy-1H-2-benzopyran-1,3(4H)-dione | HCID 57893130 | — |
반응 단계
Following a literature procedure (Ind. J. Chem. Sec. B, 1986, 25B, 640-643), 2-carboxymethyl-4-methoxybenzoic acid (1.0 g; 4.8 mmol) was dissolved in a mixture of pyridine (1.4 mL) and acetic anhydride (8.6 mL; 9.3 g; 91 mmol) then stirred for 3 hours, during which time a solid had formed. The suspension was diluted with diethyl ether, filtered and the filter cake washed with diethyl ether. Yield: 905 mg (81%) of 4-acetyl-6-methoxyisochroman-1,3-dione.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08211897B2 |
| 출처 데이터셋 | uspto-grants-2012_07 |
| ORD ID | ord-4f5df93a77454e15b9faf66fe9365428 |
| 출처 메모 | uspto-grants-2012_07 |