HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl cyclobutanecarboxylate → N-({[1-(But-3-en-1-yl)cyclobutyl]methoxy}carbonyl)-3-methyl-L-valine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl cyclobutanecarboxylate | HCID 84700 | — |
| Reactant | (S)-2-((((2,2-Dimethylhex-5-en-1-yl)oxy)carbonyl)amino)-3,3-dimethylbutanoic acid | HCID 45379499 | — |
| Product | N-({[1-(But-3-en-1-yl)cyclobutyl]methoxy}carbonyl)-3-methyl-L-valine | HCID 45379501 | — |
Reaction Steps
N-{[(1-But-3-en-1-ylcyclobutyl)methoxy]carbonyl}-3-methyl-L-valine was prepared according to the procedure for N-{[(2,2-dimethylhex-5-enyl)oxy]carbonyl}-3-methyl-L-valine by using ethyl cyclobutanecarboxylate instead of ethyl isobutyrate in Step 1. LRMS (ESI) m/z 298.3 [(M+H)+; calcd for C16H28NO4: 298.2].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08216999B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-6de9149ec46241eca9f31f9e98dd3f60 |
| Source note | uspto-grants-2012_07 |