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Ethyl 1-(3-butenyl)cyclopropanecarboxylate → N-({[1-(But-3-en-1-yl)cyclopropyl]methoxy}carbonyl)-3-methyl-L-valine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl 1-(3-butenyl)cyclopropanecarboxylate | HCID 14217022 | — |
| 反応物 | (S)-2-((((2,2-Dimethylhex-5-en-1-yl)oxy)carbonyl)amino)-3,3-dimethylbutanoic acid | HCID 45379499 | — |
| 生成物 | N-({[1-(But-3-en-1-yl)cyclopropyl]methoxy}carbonyl)-3-methyl-L-valine | HCID 45379500 | — |
反応手順
N-{[(1-But-3-en-1-ylcyclopropyl)methoxy]carbonyl}-3-methyl-L-valine was prepared according to the procedure for N-{[(2,2-dimethylhex-5-enyl)oxy]carbonyl}-3-methyl-L-valine (Steps 2 and 3) by using ethyl 1-but-3-en-1-ylcyclopropanecarboxylate-instead of ethyl 2,2-dimethylhex-5-enoate in Step 2. LRMS (ESI) m/z 284.3 [(M+H)+; calcd for C15H26NO4: 284.2].
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08216999B2 |
| 出典データセット | uspto-grants-2012_07 |
| ORD ID | ord-da6f2d0836314801ae2762f07f91a81f |
| 出典メモ | uspto-grants-2012_07 |