5-Hexen-1-ol → HCID 57431199, compound

HRID 1511582Notes

Reaction equation

HRID 1511582 reaction equation
CC(C)(C)[C@@H](C(O)=O)N[C:5]([O:7][CH2:8][CH2:9][CH2:10][CH:11]=[CH2:12])=[O:6].[NH2:18][C@@H:19]([CH2:23][C:24]([F:27])([F:26])[F:25])[C:20]([OH:22])=[O:21].[CH2:28](O)CCCC=C>>[F:25][C:24]([F:27])([F:26])[CH2:23][C@H:19]([NH:18][C:5]([O:7][CH2:8][CH2:9][CH2:10][CH2:11][CH:12]=[CH2:28])=[O:6])[C:20]([OH:22])=[O:21]

Participants

4

Reactant 3

HCID 699635-Hexen-1-olHCID 6993161(2S)-2-Amino-4,4,4-trifluorobutanoic acidHCID 453799283-Methyl-N-{[(pent-4-en-1-yl)oxy]carbonyl}-L-valine

Product 1

HCID 57431199HCID 57431199, compound

Procedure

(2S)-4,4,4-trifluoro-2-{[(hex-5-en-1-yloxy)carbonyl]amino}butanoic acid was prepared according to the procedure for 3-methyl-N-[(pent-4-enyloxy)carbonyl]-L-valine using (2S)-2-amino-4,4,4-trifluorobutanoic acid and 5-hexenol. LRMS (ESI) m/z 284.3 [(M+H)+; calcd for C11H17F3NO4: 284.1].

Sources & evidence

ORD record
ord-b11b8f8a5f30409e8fa1217df75c3761
Source dataset
uspto-grants-2012_07
Patent number
US08216999B2

Reaction notes

Loading…