反应详情

5-Methyl-2-furaldehyde (2.75 g) was gradually added by dropping, with stirring under ice cooling, to a solution prepared by dropping 3.05 g of nitromethane into 50 mL of an ice-cooled 20% aqueous solution of sodium hydroxide. After completion of the addition, the mixture was vigorously stirred for 10 minutes more to finish the reaction and the reaction solution was slowly poured over 60 mL of an ice-cooled 6N hydrochloric acid. The mixed solution was stirred for 10 minutes and the resulting separated crystals were filtered, washed with water and dried to give 2.20 g of the objective compound as yellow powder.

1. customprepared
2. additionAfter completion of the addition
3. stirringthe mixture was vigorously stirred for 10 minutes more
4. customthe reaction
5. stirringThe mixed solution was stirred for 10 minutes
6. customthe resulting separated crystals
7. filtrationwere filtered
8. washwashed with water
9. customdried