HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, 1,2-dichloro-3-fluoro- → 7-(2,3-Dichlorophenyloxy)-5-(2-fluoroethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, 1,2-dichloro-3-fluoro- | HCID 119011 | — |
| Reactant | 5-(2-Fluoroethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-7-ol | HCID 86639228 | — |
| Product | 7-(2,3-Dichlorophenyloxy)-5-(2-fluoroethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine | HCID 86639227 | — |
Reaction Steps
The same method as in Example 1 was conducted using 5-(2-fluoroethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-7-ol (Reference Example 17) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 2,3-dichloro-1-fluorobenzene instead of 1-fluoronaphthalene to give the objective compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08217031B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-b9a658db5e8640c29bc81b644334c5e9 |
| Source note | uspto-grants-2012_07 |