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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1511637Generated: October 25, 2026

3-Fluorobenzonitrile → 4-(3-Cyanophenyloxy)-6-methyl-4,5,6,7-tetrahydrofuro[2,3-c]pyridine

https://huagongshe.com/reaction/1511637

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-FluorobenzonitrileHCID 67880—
Reactant6-Methyl-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-4-olHCID 13365156—
Product4-(3-Cyanophenyloxy)-6-methyl-4,5,6,7-tetrahydrofuro[2,3-c]pyridineHCID 68412174—

Reaction Steps

The same method as in Example 1 was conducted using 6-methyl-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-4-ol (Reference Example 1) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 3-fluorobenzonitrile instead of 1-fluoronaphthalene to give the objective compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08217031B2
Source datasetuspto-grants-2012_07
ORD IDord-4cf7fe18948b4cf89ad545f9986dfd97
Source noteuspto-grants-2012_07