4-Chloro-3,5-dimethylphenol → HCID 68410472, compound

HRID 1511643Notes

Reaction equation

HRID 1511643 reaction equation
[CH3:1][C:2]1[O:12][C:5]2[CH2:6][N:7]([CH3:11])[CH2:8][CH:9]([OH:10])[C:4]=2[CH:3]=1.[Cl:13][C:14]1[C:19]([CH3:20])=[CH:18][C:17](O)=[CH:16][C:15]=1[CH3:22]>>[ClH:13].[Cl:13][C:14]1[C:19]([CH3:20])=[CH:18][C:17]([O:10][CH:9]2[CH2:8][N:7]([CH3:11])[CH2:6][C:5]3[O:12][C:2]([CH3:1])=[CH:3][C:4]2=3)=[CH:16][C:15]=1[CH3:22]

Participants

3

Reactant 2

HCID 27234-Chloro-3,5-dimethylphenolHCID 13365215HCID 13365215, compound

Product 1

HCID 68410472HCID 68410472, compound

Procedure

The same method as in Example 47 was conducted using 2,6-dimethyl-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-4-ol (Reference Example 2) instead of 6-methyl-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-4-ol (Reference Example 1) and was conducted using 4-chloro-3,5-dimethylphenol instead of 4-chloro-3-methylphenol to give the objective compound.

Workup

  1. customto give the objective compound

Sources & evidence

ORD record
ord-8e2fed97feec45c580e517abcd9d93f2
Source dataset
uspto-grants-2012_07
Patent number
US08217031B2

Reaction notes

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