4-Chloro-3,5-dimethylphenol → HCID 68410050, compound

HRID 1511657Notes

Reaction equation

HRID 1511657 reaction equation
[CH3:1][N:2]1[CH2:8][CH2:7][CH:6]([OH:9])[C:5]2[S:10][CH:11]=[CH:12][C:4]=2[CH2:3]1.[Cl:13][C:14]1[C:19]([CH3:20])=[CH:18][C:17](O)=[CH:16][C:15]=1[CH3:22]>>[ClH:13].[Cl:13][C:14]1[C:19]([CH3:20])=[CH:18][C:17]([O:9][CH:6]2[CH2:7][CH2:8][N:2]([CH3:1])[CH2:3][C:4]3[CH:12]=[CH:11][S:10][C:5]2=3)=[CH:16][C:15]=1[CH3:22]

Participants

3

Reactant 2

HCID 27234-Chloro-3,5-dimethylphenolHCID 68410490HCID 68410490, compound

Product 1

HCID 68410050HCID 68410050, compound

Procedure

The same method as in Example 47 was conducted using 5-methyl-5,6,7,8-tetrahydro-4H-thieno[3,2-c]azepin-8-ol (Reference Example 25) instead of 6-methyl-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-4-ol (Reference Example 1) and was conducted using 4-chloro-3,5-dimethylphenol instead of 4-chloro-3-methylphenol to give the objective compound.

Workup

  1. customto give the objective compound

Sources & evidence

ORD record
ord-972b46578fee4668818f55744faf20b9
Source dataset
uspto-grants-2012_07
Patent number
US08217031B2

Reaction notes

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