4-Chloro-1-naphthol → HCID 68411821, compound

HRID 1511658Notes

Reaction equation

HRID 1511658 reaction equation
[CH3:1][N:2]1[CH2:8][CH2:7][CH:6]([OH:9])[C:5]2[S:10][CH:11]=[CH:12][C:4]=2[CH2:3]1.[Cl:13][C:14]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[C:17](O)=[CH:16][CH:15]=1>>[ClH:13].[Cl:13][C:14]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[C:17]([O:9][CH:6]2[CH2:7][CH2:8][N:2]([CH3:1])[CH2:3][C:4]3[CH:12]=[CH:11][S:10][C:5]2=3)=[CH:16][CH:15]=1

Participants

3

Reactant 2

HCID 117874-Chloro-1-naphtholHCID 68410490HCID 68410490, compound

Product 1

HCID 68411821HCID 68411821, compound

Procedure

The same method as in Example 47 was conducted using 5-methyl-5,6,7,8-tetrahydro-4H-thieno[3,2-c]azepin-8-ol (Reference Example 25) instead of 6-methyl-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-4-ol (Reference Example 1) and was conducted using 4-chloro-1-naphthol instead of 4-chloro-3-methylphenol to give the objective compound.

Workup

  1. customto give the objective compound

Sources & evidence

ORD record
ord-ab8118457366402fa354ef837c371375
Source dataset
uspto-grants-2012_07
Patent number
US08217031B2

Reaction notes

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