Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzene, 1-fluoro-4-(trifluoromethyl)- → 2,7-Dimethyl-4-[4-(trifluoromethyl)phenyloxy]-5,6,7,8-tetrahydro-4h-furo[2,3-c]azepine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzene, 1-fluoro-4-(trifluoromethyl)- | HCID 67873 | — |
| 반응물 | 2,7-dimethyl-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepin-4-ol | HCID 68410119 | — |
| 생성물 | 2,7-Dimethyl-4-[4-(trifluoromethyl)phenyloxy]-5,6,7,8-tetrahydro-4h-furo[2,3-c]azepine | HCID 68410744 | — |
반응 단계
The same method as in Example 1 was conducted using 2,7-dimethyl-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepin-4-ol (Reference Example 20) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 4-fluoro benzotrifluoride instead of 1-fluoronaphthalene to give the objective compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08217031B2 |
| 출처 데이터셋 | uspto-grants-2012_07 |
| ORD ID | ord-9ee0073831d14f288b64c92ad6c8119c |
| 출처 메모 | uspto-grants-2012_07 |