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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1511672Erstellt: 26. Oktober 2026

1-Chloro-3-fluoro-2-(trifluoromethyl)benzene → 4-[3-Chloro-2-(trifluoromethyl)phenyloxy]-6-methyl-5,6,7,8-tetrahydro-4H-thien o[2,3-d]azepine

https://huagongshe.com/reaction/1511672

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1-Chloro-3-fluoro-2-(trifluoromethyl)benzeneHCID 16743980—
Edukt6-methyl-5,6,7,8-tetrahydro-4H-thieno[2,3-d]azepin-4-olHCID 68409998—
Produkt4-[3-Chloro-2-(trifluoromethyl)phenyloxy]-6-methyl-5,6,7,8-tetrahydro-4H-thien o[2,3-d]azepineHCID 68413205—

Reaktionsschritte

The same method as in Example 1 was conducted using 6-methyl-5,6,7,8-tetrahydro-4H-thieno[2,3-d]azepin-4-ol (Reference Example 28) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 2-chloro-6-fluorobenzotrifluoride instead of 1-fluoronaphthalene to give the objective compound.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08217031B2
Quelldatensatzuspto-grants-2012_07
ORD IDord-bf4c692414174be0a276a7f194dc085b
Quellennotizuspto-grants-2012_07