1,2,3-Tribromo-4-fluorobenzene → HCID 68411858, compound

HRID 1511675Notes

Reaction equation

HRID 1511675 reaction equation
[O:1]1[C:5]2[CH2:6][NH:7][CH2:8][CH:9]([OH:10])[C:4]=2[CH:3]=[CH:2]1.[Br:11][C:12]1[C:17]([Br:18])=[C:16]([Br:19])[CH:15]=[CH:14][C:13]=1F>>[Br:11][C:12]1[C:17]([Br:18])=[C:16]([Br:19])[CH:15]=[CH:14][C:13]=1[O:10][CH:9]1[CH2:8][NH:7][CH2:6][C:5]2[O:1][CH:2]=[CH:3][C:4]1=2

Participants

3

Reactant 2

HCID 541915681,2,3-Tribromo-4-fluorobenzeneHCID 55300160HCID 55300160, compound

Product 1

HCID 68411858HCID 68411858, compound

Procedure

The same method as in Example 1 was conducted using 4,5,6,7-tetrahydrofuro[2,3-c]pyridin-4-ol (Reference Example 4) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 2,3,4-tribromo-1-fluorobenzene instead of 1-fluoronaphthalene 1 to give the objective compound.

Workup

  1. customto give the objective compound

Sources & evidence

ORD record
ord-2e5df4b8e4b24e14abebdec050c36e69
Source dataset
uspto-grants-2012_07
Patent number
US08217031B2

Reaction notes

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